Probiotic treatment for antibiotic associated diarrhea (AAD) has been well studied. Evidence supports specific probiotic recommendations for AAD, based upon four criteria: (a) the appropriate probiotic by species and strain (brand name), (b) dose strength, (c) administration timing, and (d) duration of treatment. The goal of my doctoral capstone project was to enhance healthcare providers‘ (HCP) knowledge and use of probiotics as part of the management regimen for AAD. Based on the Academic Center for Evidence-based Practice (ACE) Star Model of Knowledge Transformation (Stevens, 2004), an educational program on concurrent antibiotic and probiotic use was developed and made available to clinicians. The effectiveness of the educational offering was measured by pre-education and post-education chart reviews that assessed the probiotic recommendation for the clinicians‘ patients. A pre- and post-education phone call log was also assessed for the volume of calls from patients with AAD. Each HCP‘s probiotic recommendations were measured by the four criteria and were analyzed separately. Based on Fischer‘s Exact Test, the overall effect of the brief educational offering never reached statistical significance in any category. This project never obtained the targeted 80% appropriate probiotic recommendation. Overall, the four criteria measurements were the appropriate probiotic by species and strain (brand name) 4.54% (4/88) p = 0.52 the dose strength 5.68% (5/88) p = 0.5808 the administration timing 3.40% (3/88) p = 1 and the duration of treatment 4.54% (4/88) p = 0.5818 (α = 0.05). The documented recommendation rate for any probiotic was only 10.2% (9/88). A follow-up structured interview with each of the HCPs, indicated that the documentation of a probiotic recommendation may not have been reflective of the actual recommendation rate. Probiotic recommendations were often not charted, given in conversation, or patients received a clinic designed probiotic informational handout. These results support that changing prescribing habits is a challenging and difficult task. An hour-long PowerPoint in-service, handouts, pocket reference card, 17 x 11 in. office display and seven days of audit and feedback are insufficient to do so in this particular setting. However, chart review may not have captured all probiotic recommendations since the HCPs‘ indicated that not all were documented.