In the past forty years there has been great progress in developing and laying foundation for the nurse practitioner (NP) role; yet there is more to be done to fully engage and integrate NP practice with that of physician colleagues. The literature consistently describes the advantages of effective provider collaboration to outcomes in healthcare, as well as the barriers to provider collaboration, including physician resistance and lack of physician knowledge on the NP role. Nursing is poised and has a responsibility to engage a dialogue with physicians on the nurse practitioner role and provide perspective on optimal physician–NP collaboration that helps meet the current challenges in healthcare. A web-based, self-study continuing medical education (CME) program for physicians on NP education, philosophy and practice will be developed using an online format. The program was available on The University of Nebraska Medical Center CME website for all licensed Medical Doctor’s and Doctors of Osteopathy in Nebraska. This program adds a key voice to healthcare’s chorus on interprofessional education and contributes new and important perspectives to interprofessional collaboration being emphasized in medical and nurses training, regulatory policies, health organizational strategies and actual work practices among physicians and NPs. This capstone project is focused on the development, implementation and evaluation of a CME program for physicians on the nurse practitioner role and facilitation of physician openness to collaboration with NPs. The study’s outcomes are limited due to participant response rate, but suggest physicians lack knowledge of the NP role, as well as a lack of awareness for the need to know more about NPs and collaboration with NPs. The issue of physician openness to engaging NPs in practice requires both additional research work; the use of educational and cultural change strategies; and direct-response data collection methods.