The rate of maternal mortality in developing countries remains unacceptably high. The ratio of maternal deaths is over 4.5 times higher in Guatemala than in the United States, while the lifetime risk of maternal death for a woman in Guatemala is ten times higher than for a woman in the United States. Postpartum hemorrhage (PPH) is the most common cause of these excessively high maternal mortality rates in developing countries. In Guatemala, hemorrhage accounts for over half of maternal deaths. Since traditional birth attendants (TBAs) remain the primary provider of maternal care in many rural Guatemalan Mayan villages, efforts need to be made to educate the TBAs in the identification and treatment of PPH in order to impact timely referral to health care facilities and lower maternal mortality. The Home Based Life Saving Skills (HBLSS) course has been shown to be a successful learning tool in other settings for teaching about emergency management of PPH. The purpose of the project was to determine if an educational course adapted from the HBLSS educational module on prevention and treatment of PPH taught to TBAs and community members in two indigenous Mayan villages in Guatemala would increase their knowledge of prevention and treatment of PPH, including indications for referral. Data on demographics were obtained, and pre and post course knowledge was measured. For the combined groups, the mean score for both sections, prevention and treatment, increased after presentation of the course. For one village, there was a significant difference between pre and post test scores for both the prevention and treatment checklists. Neither of the pre-post differences was significant for the other village. These findings need to be reproduced in additional Guatemalan Mayan villages.